An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration.
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چکیده
منابع مشابه
An activating mutation in a Caenorhabditis elegans Gs protein induces neural degeneration.
Heterotrimeric guanine nucleotide-binding proteins (G proteins) act as signal-transducing molecules that connect serpentine-transmembrane receptors to a variety of intracellular effectors. We characterized a Caenorhabditis elegans G(s) gene, gsa-1, which encodes a G(s) alpha-subunit (G alpha(s)) that is expressed throughout the nervous system and in muscle cells. gsa-1 is an essential gene; a l...
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ژورنال
عنوان ژورنال: Genes & Development
سال: 1997
ISSN: 0890-9369
DOI: 10.1101/gad.11.12.1493